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John Smither

John Smither

Chief Financial Officer

John W. Smither served as Sienna’s CFO from January 2016 to March 2017, and subsequently has served as an independent consultant in the biopharmaceutical industry. Previously, he served as CFO of Kythera Biopharmaceuticals, Inc. from November 2007 until it was acquired by Allergan in October 2015 for $2.1 billion. As CFO of Kythera, Mr. Smither oversaw multiple private and public financing rounds, including Kythera’s initial public offering and subsequent follow-on offerings.

From 1998 to 2007, Mr. Smither held various positions at Amgen. From 2001 to 2004, he served as vice president of finance and administration for Amgen’s European Division, where he was responsible for financial operations in 28 European countries. Prior to that, Mr. Smither served as head of internal audit, and following his time in Europe was executive director of corporate accounting. Prior to joining Amgen, he served as audit partner at Ernst & Young LLP, a public accounting firm, and following his time at Ernst & Young served as CFO of several early stage companies. Mr. Smither has served on the board of directors of Achaogen, Inc. since December 2013, where he currently serves as the audit committee chair and a member of the compensation committee. He holds a BS in Business Administration from California State University, Los Angeles. Mr. Smither is a Certified Public Accountant (inactive) and a member of the American Institute of Certified Public Accountants, the California Society of Certified Public Accountants and Financial Executives International.